What is Phenobarbital, and what is it used for?
Phenobarbital is a drug from the barbiturate group. Phenobarbital 100 mg is used to treat:
- Epilepsy (seizures that affect the whole body);
- Minor impulsive epilepsy (a special form of epilepsy with small muscle twitches)
Phenobarbital for seizures
Studies have shown the effectiveness of Phenobarbital in preventing all types of seizures except absences.
Phenobarbital for sleep
Phenobarbital is also effective in the treatment of insomnia (sleep disturbances) and as a sedative to reduce the symptoms of anxiety.
Buying phenobarbital online procedure is fast and does not require much effort, the purchase is completed promptly, and you can quickly begin therapy.
Mechanism of action of Phenobarbital
The active ingredient targets specific binding sites in the brain, thereby strengthening the action of endogenous relaxants and reducing the uncontrolled transmission of electrical signals in the brain cells. This reduces excessive reactions, spasms, and impaired consciousness.
Absorption into the body after ingestion is almost one hundred percent. The highest concentration of Phenobarbital in the blood is seen after 6-18 hours. The half-life is 3-7 days in infants, 3 days in children, and 2-4 days in adults.
Since the dosage of the drug depends on various factors, it is recommended that it be used as recommended by your doctor. The following are average doses.
Phenobarbital: Administration schedule
For the treatment and prevention of seizures, Phenobarbital is administered according to the following schedule.
Adults: 50 to 100 mg of Phenobarbital 2-3 times a day. The maximum dose is 600 mg.
Children: 15 to 50 mg 2-3 times a day.
When treating insomnia as a sedative, the schedule for taking the drug is as follows.
Adults: 100 to 200 mg of Phenobarbital before bedtime. The recommended dose for adults as a sedative is 30-90 mg per day divided into several doses.
Children: The dose of Phenobarbital as a sedative is 2 mg per kilogram of body weight in children. A form of suspension or syrup is recommended for this purpose.
Phenobarbital: Overdose symptoms
Overdose results in the following symptoms: nystagmus, unusual eye movements, weakness/sleepiness, ataxia, confusion, slurred speech, dizziness, headache, impaired reflexes, weakened reflexes, depressed breathing, constricted pupils, tachycardia, hypotension, weak pulse, cold and clammy skin.
What are the side effects of Phenobarbital?
The following side effects may occur when taking Phenobarbital:
Gastrointestinal problems (nausea, vomiting, diarrhea, constipation, abdominal pain), headache, dizziness, fatigue, drowsiness, poor coordination, delirium (confusion), depression, suicidal thoughts, and difficulty concentrating.
Skin hypersensitivity reactions (increased skin photosensitivity, rashes), low blood pressure, labored breathing, kidney damage, liver damage, etc. may also occur.
Does Phenobarbital cause weight gain?
It is not scientifically proven that Phenobarbital can cause weight gain. However, each patient may have an individual reaction, so if you see any changes or side effects, you should always contact your doctor.
What are Phenobarbital interactions?
Phenobarbital may interact with the following substances and medicines:
- angiotensin-converting enzyme inhibitors;
- angiotensin receptor blockers;
- antifungal drugs;
- birth control pills;
- calcium channel blockers;
- oral corticosteroids;
- anti-diabetic drugs Gliptin;
- antiviral drugs against hepatitis C;
- certain HIV medications.
All possible interactions are listed. Be sure to consult a pharmacist or physician before starting therapy.
Contraindications of Phenobarbital
Phenobarbital should not be taken if you are allergic to the active ingredient, other barbiturates, or any other ingredients of the drug.
Particular caution is required when taking Phenobarbital if the patient has acute liver failure; various malfunctions of the kidneys; or heart disease.
Administration of the drug is not recommended during pregnancy and lactation. The drug penetrates the placenta to the fetus, through the blood into the milk, and may cause undesirable effects on the child.
Buying Phenobarbital online
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